Top 10 Medical Strains with High CBD Percentage

Top 10 Medical Strains with High CBD Percentage

Due to their potential health benefits, cannabis strains with high CBD content have come to the front of the line with the medical community. A nonpsychoactive compound in cannabis, CBD (Cannabidiol) has been shown to have an array of therapeutic effects while devoid of the “high” that’s associated with THC. From supplying you with pain relief to assuaging anxiety to implementing all-around wellness support, CBD-rich strains are a natural wellspring.

Here, we’d like to share our top 10 medical cannabis strains packed with high percentages of CBD, which are best suited for those who want to include CBD into their healthcare routine.

1. Charlotte’s Web

Charlotte’s Web is one of the most famous high CBD strains, that was bred specifically for its medical uses. This strain is named after a young girl who saw relief from seizures, this strain has a high percentage of CBD and almost none of THC, making it much more powerful due to its lack of psychoactive attributes. Used to treat epilepsy, anxiety, and chronic pain, it is commonly used.

2. ACDC

ACDC is another well-known CBD-rich strain that offers a 20:1 ratio of CBD to THC. ACDC has little or no psychoactive effects and provides patients with significant therapeutic relief. People who struggle with pain, inflammation, or muscle spasms tend to benefit especially from it. Because of this strain’s high CBD content, great for naturally non-psychoactive relief.

3. Harlequin

A Sativa dominant strain, Harlequin has a well-balanced CBD to THC ratio, giving them just the right amount of the peace they need without feeling too much tired. This strain is high in CBD and is good for pain, anxiety, and stress. So Harlequin is known for being a good feel-good drug, also making it a popular daytime drug.

4. Ringo’s Gift

Ringo’s Gift is a hybrid strain named for CBD activist Lawrence Ringo and known for a high CBD percentage that can sometimes cross 15-20%. It’s well known to be a good stress reliever and is often used to treat stress, anxiety, and chronic pain. Smooth, mellow effects with a mild THC content make this perfect for users who want the therapeutic benefits without any intoxicating effects.

5. Cannatonic

Cannatonic is another strain with a notable CBD-to-THC ratio of 1:With concentrations of 1 or higher, a medical user will get the therapeutic benefits of CBD as well as a slight psychoactive ‘kick’ from THC. With its high CBD content, it helps with pain, inflammation, and anxiety and is an ideal gentle and balanced for those with CBD looking.

6. Pennywise

Pennywise is an Indica-dominant hybrid strain with a high level of CBD/THC balance. There are high CBD percentages, usually 10 – 15%. This strain is very relaxing and good for those with stress, insomnia, and chronic pain due to its mild THC content, meaning they don’t feel overly sedated.

7. CBD Shark

Hybrid of CBD Shark strain features high CBD content in some phenotypes reaching over 20%. A popular CBD product most often used for anxiety, depression, and chronic pain, CBD Shark is renowned for its calming and relaxing effects. For those suffering from natural, non-psychoactive relief, it is perfect.

8. Suzy Q

The sativa-dominant hybrid Suzy Q is known for serving high levels of CBD with little THC. This strain is exactly what you’re looking for regarding relief from inflammation, pain, and anxiety, which makes its high CBD portion a pretty attractive thing. It is especially well known for its calming of the mind and body with no sedative side effects and is therefore perfect for daytime use.

9. Harle-Tsu

Harle-Tsu is a cross between Harlequin and Sour Tsunami and is another strain with a fairly high CBD content, frequently up to 18%. This hybrid strain is perfect for those who are looking for relief in their pain, anxiety, and muscle spasms. This is a balanced nature which is attributed to its offering by the users who need the therapeutic effects but not the psychological blur.

10. Sour Tsunami

Sour Tsunami is one of the first strains to be bred particularly for high CBD levels; it’s particularly useful for medical cannabis users. An ideal CBD percentage present in this strain is 10-15% which can effectively treat chronic pain, stress, and inflammation. Sour Tsunami has only minimal THC, but a very gentle, soothing effect, making it ideal for therapeutic use.

Why Choose High CBD Strains?

More and more people are choosing high CBD strains to get benefits from medical usage without having to experience the intoxicating effects of THC. CBD has been used in different medical conditions with the help of which is pain, anxiety, epilepsy, and inflammation. In addition, CBD-rich cannabis strains are nonpsychoactive, meaning that they can’t provide you with high.

These strains help users reap the benefits of cannabis without the effects of the active ingredient causing them to lose focus. If you’re thinking about adding CBD to your wellness routine, these top 10 strains are a great place to start.

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Conclusion

CBD-rich strains are growing more and more popular because they are so effective for wellness without the psychoactive effects of THC. The best top 10 high CBD strains that will provide you the natural relief from pain, anxiety, inflammation, and much more. Always consult with a healthcare professional when picking a cannabis strain, but remember they’re always different, so here’s the full breakdown.

CertaMD Editorial Team
CertaMD's Editorial Team consists of seasoned medical professionals and writers dedicated to delivering accurate, up-to-date health information, including insights on medical cannabis. With a commitment to excellence, they ensure content is both accessible and authoritative for healthcare consumers.

Important Medical Information & Disclaimers

Medical disclaimer

The information on this CertaMD page is provided for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

All medical marijuana evaluations and recommendations through CertaMD are performed exclusively by licensed U.S. healthcare providers using secure telemedicine technology, in accordance with applicable state laws and regulations.

Always speak with a qualified physician or other licensed healthcare professional before making decisions about your health, changing existing medications, or starting any new treatment, including medical cannabis.

Source: FDA – Cannabis Research & Drug Approval Process

Individual results and treatment response

Medical cannabis does not work the same way for every patient. Symptom relief can depend on factors such as the type of product (THC/CBD ratio, route of administration), dose, frequency of use, underlying medical conditions, concurrent medications, and lifestyle variables like diet, stress, and sleep.

Because response and tolerability vary, ongoing follow-up with your CertaMD provider is important to review benefits, monitor side effects, and adjust your treatment plan safely over time.

Source: NIH – Therapeutic Effects of Cannabis and Cannabinoids

Possible risks and side effects

Like any therapeutic option, medical marijuana can cause side effects. Commonly reported effects include dry mouth, dizziness, fatigue, red or irritated eyes, increased appetite, headache, and temporary problems with attention, concentration, or short-term memory.

Some patients, especially with higher-THC products, may experience anxiety, rapid heartbeat, worsened mood, or perceptual changes; in rare cases, serious effects such as psychosis, significant mood changes, heart rhythm disturbances, or cannabinoid hyperemesis syndrome (recurrent nausea and vomiting) have been reported. If you notice severe, unexpected, or persistent symptoms, stop using cannabis and contact your healthcare provider or seek urgent care.

Source: Mayo Clinic – Marijuana: Safety and Side Effects

Legal and regulatory notice

Medical marijuana programs are created and regulated at the state level, and eligibility, product access, and telemedicine rules vary by jurisdiction. Under U.S. federal law, marijuana remains a Schedule I controlled substance, and clinicians typically “recommend” or “certify” medical cannabis use rather than prescribe it in the traditional sense.

Some states require an initial in-person visit before medical cannabis certification, while others allow both initial and renewal evaluations via telehealth; CertaMD operates within the specific requirements of each state it serves.

Sources: DEA – Controlled Substances Act

Telehealth.org – Cannabis Prescribing and Telehealth

Product quality, sourcing, and safety

For your safety, use only medical cannabis products obtained from licensed, state-regulated dispensaries that perform appropriate laboratory testing for potency and contaminants. Unregulated or illicit products may contain pesticides, heavy metals, microbes, or inaccurate THC/CBD concentrations, which can increase health risks and lead to unpredictable effects.

Ask your CertaMD clinician or dispensary pharmacist about product selection, dosing, onset and duration of effects, and how to store products safely away from children and pets.

Source: FDA – What to Know About Cannabis Products

Reporting adverse events and safety concerns

If you experience serious or unexpected side effects while using medical cannabis, contact your healthcare provider immediately or seek emergency care when appropriate.

Patients and caregivers in the United States can also report adverse events and product problems to the FDA’s MedWatch program online or by phone at
1-800-FDA-1088, which helps regulators monitor safety trends and protect public health.

Source: FDA – MedWatch Safety & Adverse Event Reporting

See how much you could save with a medical card

Note that this is an estimate of savings and does not constitute a guarantee. Additional taxes in your area or recent changes in local laws may affect these rates. Please verify current regulations in your state.

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